Karoline-Marie Bornemann is a computational biomedical engineer specialized in cardiovascular fluid dynamics with a background in aerospace engineering. Her research focuses on the computational modeling of heart valves using fluid-structure interaction simulations. Her long-term research goal is to use numerical modeling to understand complex cardiovascular pathophysiology and answer relevant clinical questions. During her PhD, she investigated the onset of turbulence past bioprosthetic valve prostheses in adults. Given the significant lack of cardiovascular research in pediatrics, she decided to apply my knowledge in the modeling of valve prostheses to tackle highly complex and patient-specific problems of congenital heart diseases. At Stanford University, she applies her obtained skill set to the computational modeling of congenital valve diseases and valve repair within an interdisciplinary team combining the individual strengths of both engineers and clinicians. Her research differs from the mainstream as she uses her strong fundamental background in aerospace engineering to bridge the two worlds of highly sophisticated computational simulations and daily clinical practice guided by the mission to improve children’s health.